Several years ago, I attended the International Society for Medical Publishing Professionals (ISMPP) annual meeting. As a presenter, I was introducing attendees to a new initiative called CrossCheck. Our company, iParadigms, had recently partnered with CrossRef, a non-profit providing several services to the scholarly publishing community including Digital Object Identifier (DOI) registration. The partnership was straightforward. CrossRef's publisher and society members would receive access to iThenticate for use in editorial review in return for allowing us to index their published content. Where plagiarism detection software is concerned, the primary value is the world of content against which you can compare manuscripts. My introduction of the CrossCheck initiative received mixed reviews. Many wondered how the use of our software would impact existing editorial processes. Would efficiencies be affected? Would the scholarly research community support the effort?